Case Study
Building a Launch GEO Baseline
How a specialty pharma brand established AI visibility pre-launch, identified competitive gaps, and improved share-of-answer by 16 percentage points.
Last updated: January 2026
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Snapshot
- Brand Type
- Specialty pharmaceutical
- Therapeutic Area
- Autoimmune / Immunology
- Stage
- Pre-launch (6 months to approval)
- Geography
- United States
- Time Window
- 12-week monitoring period
- LLMs Monitored
- ChatGPT, Claude, Gemini, Perplexity
The Challenge
A specialty pharma company was preparing to launch a new therapy for a moderate-to-severe autoimmune condition. The competitive landscape included three established brands with significant market presence and marketing investment.
The brand team faced several concerns:
- Unknown AI positioning: With over 40 million daily health queries on ChatGPT alone[2], patients and HCPs were already asking about treatment options. The team didn't know how (or if) AI systems mentioned their therapy, even pre-approval.
- Competitor advantage: Established competitors had years of published content, clinical data, and source footprint. Their therapies appeared prominently in AI answers; the new brand was largely invisible.
- Accuracy concerns: Pre-launch buzz and early clinical publications meant AI might already be making claims about the therapy - potentially inaccurate ones based on incomplete information.
- Launch readiness: The team needed a clear picture of AI visibility before launch to prioritize content investments and ensure approved messaging would be reflected in AI answers.
What AI Pulse Found
AI Pulse ran a baseline analysis with 120 question variations covering patient intent (treatment options, side effects, cost, lifestyle) and HCP intent (mechanism, efficacy, dosing, guidelines) across all four major LLMs.
Visibility Gap
The initial baseline revealed significant visibility gaps:
- Mention rate (all providers)
- 62%
- Competitor A mention rate
- 94%
- Competitor B mention rate
- 89%
- Ranking position (when mentioned)
- 3.2 avg (often 3rd or 4th)
When the brand was mentioned, it typically appeared after two or three competitors, positioning it as an also-ran rather than a viable first-line option.
Positioning Issues
Beyond visibility, the Influence Graph revealed why competitors dominated:
- Competitors had 40+ high-authority sources (journal articles, medical education sites, treatment guidelines) being cited by AI.
- The new brand had only 8 citable sources, mostly early clinical trial publications and a corporate press release.
- AI framing used competitor language: "established treatment options include..." with the new therapy mentioned as "an emerging option" or "in late-stage trials."
Compliance Flags
PI-backed verification identified 14 claims requiring attention:
4 Not-in-PI Claims
- • Efficacy comparison to competitor (no head-to-head data)
- • Duration of response claim (beyond approved labeling)
- • Off-label dosing suggestion for pediatric use
- • Safety claim contradicting known warnings
10 Ambiguous Claims
Mostly related to mechanism of action phrasing and comparative positioning that, while not explicitly wrong, introduced compliance uncertainty.
The Not-in-PI claims were especially concerning: AI was making statements about the therapy that couldn't be defended with approved labeling[3, 4].
Actions Taken
The brand team used the governance queue to route findings to appropriate owners:
- Medical Affairs (Not-in-PI claims): Immediate review of the 4 Not-in-PI claims. Medical wrote clarifying content for publication on medical education sites and coordinated with clinical teams to address the off-label dosing concern appearing in AI answers.
- Brand Marketing (visibility gaps): Prioritized content investments to build source footprint. Published 6 new pieces of educational content on high-authority partner sites, refreshed the mechanism of action explainer, and worked with KOLs on accessible publications.
- Omnichannel (positioning alignment): Reviewed all approved content to ensure consistent positioning language. Updated website copy to use preferred framing that AI could learn from[6].
- Communications (narrative prep): Developed talking points for inevitable questions about AI accuracy. Documented baseline findings to show proactive monitoring.
Retest Outcome
After 8 weeks of content publishing and source building, AI Pulse reran the baseline question sets. Results:
Mention Rate
62% → 78%
+16 percentage points
Ranking Position
3.2 → 2.1 avg
Now typically 2nd, not 3rd/4th
Not-in-PI Claims
4 → 1
3 resolved, 1 in progress
High-Authority Citations
8 → 17
+9 new citable sources
The brand entered launch with a documented AI visibility baseline, clear competitive positioning, and an ongoing monitoring program to catch drift early.
What Changed Operationally
Beyond metrics, the engagement changed how the team operated:
- AI visibility became a KPI: Share-of-answer joined share-of-voice in brand performance dashboards. Monthly reports now include AI Pulse scores.
- Content strategy expanded: The content calendar now explicitly includes "source footprint" goals - not just impressions or engagement, but whether content is likely to be cited by AI systems.
- MLR workflow improved: Not-in-PI findings created a fast-track review process for corrective content. Audit trails made compliance documentation straightforward.
- Cross-functional alignment: Brand, Medical, Omnichannel, and Comms now have a shared view of AI positioning - reducing silos and enabling faster response to drift[6].
Disclaimer
Anonymized Composite: This case study is a composite example based on common scenarios encountered by pharmaceutical brand teams. Company names, specific metrics, and details have been generalized and anonymized. It is intended for illustration purposes to demonstrate typical AI monitoring challenges and outcomes, not to represent a specific client engagement.
Citations
- [1] OpenAI - Introducing ChatGPT Health (Jan 7, 2026) https://openai.com/index/introducing-chatgpt-health/
- [2] Healthcare Dive - More than 40 million people ask ChatGPT healthcare questions every day (Jan 6, 2026) https://www.healthcaredive.com/news/40-million-use-chatgpt-health-questions-openai/808861/
- [3] Covington - 2023 End-of-Year Summary of FDA Advertising and Promotion Enforcement Activity (Jul 22, 2024) https://www.cov.com/en/news-and-insights/insights/2024/07/2023-end-of-year-summary-of-fda-advertising-and-promotion-enforcement-activity
- [4] FDA OPDP The Brief Summary (Jan 2025 PDF) https://www.fda.gov/media/185040/download
- [5] IQVIA case study - predictive field alerts 36% Rx uplift (Dec 26, 2023) https://www.iqvia.com/library/case-studies/predictive-field-alerts-driving-rx-lift-and-roi-in-autoimmune-treatment
- [6] ZS - Unified engagement / omnichannel context (Apr 15, 2025) https://www.zs.com/insights/unified-engagement-goal-pharma-marketing