Case Study

Building a Launch GEO Baseline

How a specialty pharma brand established AI visibility pre-launch, identified competitive gaps, and improved share-of-answer by 16 percentage points.

Last updated: January 2026

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Snapshot

Brand Type
Specialty pharmaceutical
Therapeutic Area
Autoimmune / Immunology
Stage
Pre-launch (6 months to approval)
Geography
United States
Time Window
12-week monitoring period
LLMs Monitored
ChatGPT, Claude, Gemini, Perplexity

The Challenge

A specialty pharma company was preparing to launch a new therapy for a moderate-to-severe autoimmune condition. The competitive landscape included three established brands with significant market presence and marketing investment.

The brand team faced several concerns:

  • Unknown AI positioning: With over 40 million daily health queries on ChatGPT alone[2], patients and HCPs were already asking about treatment options. The team didn't know how (or if) AI systems mentioned their therapy, even pre-approval.
  • Competitor advantage: Established competitors had years of published content, clinical data, and source footprint. Their therapies appeared prominently in AI answers; the new brand was largely invisible.
  • Accuracy concerns: Pre-launch buzz and early clinical publications meant AI might already be making claims about the therapy - potentially inaccurate ones based on incomplete information.
  • Launch readiness: The team needed a clear picture of AI visibility before launch to prioritize content investments and ensure approved messaging would be reflected in AI answers.

What AI Pulse Found

AI Pulse ran a baseline analysis with 120 question variations covering patient intent (treatment options, side effects, cost, lifestyle) and HCP intent (mechanism, efficacy, dosing, guidelines) across all four major LLMs.

Visibility Gap

The initial baseline revealed significant visibility gaps:

Mention rate (all providers)
62%
Competitor A mention rate
94%
Competitor B mention rate
89%
Ranking position (when mentioned)
3.2 avg (often 3rd or 4th)

When the brand was mentioned, it typically appeared after two or three competitors, positioning it as an also-ran rather than a viable first-line option.

Positioning Issues

Beyond visibility, the Influence Graph revealed why competitors dominated:

  • Competitors had 40+ high-authority sources (journal articles, medical education sites, treatment guidelines) being cited by AI.
  • The new brand had only 8 citable sources, mostly early clinical trial publications and a corporate press release.
  • AI framing used competitor language: "established treatment options include..." with the new therapy mentioned as "an emerging option" or "in late-stage trials."

Compliance Flags

PI-backed verification identified 14 claims requiring attention:

4 Not-in-PI Claims

  • • Efficacy comparison to competitor (no head-to-head data)
  • • Duration of response claim (beyond approved labeling)
  • • Off-label dosing suggestion for pediatric use
  • • Safety claim contradicting known warnings

10 Ambiguous Claims

Mostly related to mechanism of action phrasing and comparative positioning that, while not explicitly wrong, introduced compliance uncertainty.

The Not-in-PI claims were especially concerning: AI was making statements about the therapy that couldn't be defended with approved labeling[3, 4].

Actions Taken

The brand team used the governance queue to route findings to appropriate owners:

  1. Medical Affairs (Not-in-PI claims): Immediate review of the 4 Not-in-PI claims. Medical wrote clarifying content for publication on medical education sites and coordinated with clinical teams to address the off-label dosing concern appearing in AI answers.
  2. Brand Marketing (visibility gaps): Prioritized content investments to build source footprint. Published 6 new pieces of educational content on high-authority partner sites, refreshed the mechanism of action explainer, and worked with KOLs on accessible publications.
  3. Omnichannel (positioning alignment): Reviewed all approved content to ensure consistent positioning language. Updated website copy to use preferred framing that AI could learn from[6].
  4. Communications (narrative prep): Developed talking points for inevitable questions about AI accuracy. Documented baseline findings to show proactive monitoring.

Retest Outcome

After 8 weeks of content publishing and source building, AI Pulse reran the baseline question sets. Results:

Mention Rate

62% → 78%

+16 percentage points

Ranking Position

3.2 → 2.1 avg

Now typically 2nd, not 3rd/4th

Not-in-PI Claims

4 → 1

3 resolved, 1 in progress

High-Authority Citations

8 → 17

+9 new citable sources

The brand entered launch with a documented AI visibility baseline, clear competitive positioning, and an ongoing monitoring program to catch drift early.

What Changed Operationally

Beyond metrics, the engagement changed how the team operated:

  • AI visibility became a KPI: Share-of-answer joined share-of-voice in brand performance dashboards. Monthly reports now include AI Pulse scores.
  • Content strategy expanded: The content calendar now explicitly includes "source footprint" goals - not just impressions or engagement, but whether content is likely to be cited by AI systems.
  • MLR workflow improved: Not-in-PI findings created a fast-track review process for corrective content. Audit trails made compliance documentation straightforward.
  • Cross-functional alignment: Brand, Medical, Omnichannel, and Comms now have a shared view of AI positioning - reducing silos and enabling faster response to drift[6].

Disclaimer

Anonymized Composite: This case study is a composite example based on common scenarios encountered by pharmaceutical brand teams. Company names, specific metrics, and details have been generalized and anonymized. It is intended for illustration purposes to demonstrate typical AI monitoring challenges and outcomes, not to represent a specific client engagement.

Citations

  1. [1] OpenAI - Introducing ChatGPT Health (Jan 7, 2026) https://openai.com/index/introducing-chatgpt-health/
  2. [2] Healthcare Dive - More than 40 million people ask ChatGPT healthcare questions every day (Jan 6, 2026) https://www.healthcaredive.com/news/40-million-use-chatgpt-health-questions-openai/808861/
  3. [3] Covington - 2023 End-of-Year Summary of FDA Advertising and Promotion Enforcement Activity (Jul 22, 2024) https://www.cov.com/en/news-and-insights/insights/2024/07/2023-end-of-year-summary-of-fda-advertising-and-promotion-enforcement-activity
  4. [4] FDA OPDP The Brief Summary (Jan 2025 PDF) https://www.fda.gov/media/185040/download
  5. [5] IQVIA case study - predictive field alerts 36% Rx uplift (Dec 26, 2023) https://www.iqvia.com/library/case-studies/predictive-field-alerts-driving-rx-lift-and-roi-in-autoimmune-treatment
  6. [6] ZS - Unified engagement / omnichannel context (Apr 15, 2025) https://www.zs.com/insights/unified-engagement-goal-pharma-marketing

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